Acidosis lactica por metformina pdf

Ingreso por dolor abdominal, diarrea, fiebre y somnolencia. Metformininduced lactic acidosis due to acute renal. Apr 04, 2019 request pdf on researchgate acidosis lactica por metformina. We discuss the pathophysiological mechanisms of lactic acidosis with particular regard to the role played by the drug as a. Metformin associated lactic acidosis is related with the used dose and underlying conditions that may lead to high serum lactate. Acidosis lactica por metformina desencadenada por una. Metforminassociated lactic acidosis is a severe and infrequent adverse event. Acidosis lactica por metformina desencadenada por una insuficiencia renal aguda. Early diagnosis is essential to start an early treatment, which often has favorable results. Metforminassociated lactic acidosis in intensive care unit. Acidosis lactica por metformina endocrinologia y nutricion elsevier. Lactic acidosis secondary to metformin should be suspected in patients who are treated with this medicine and who have risk factors such as liver and kidney failure, alcoholism and sepsis. Evaluate incidence of metformin associated lactic acidosis, admission in intensive care unit icu or medicalsurgical unit, severity of metabolic acidosis and mortality.

Aug 19, 2019 request pdf on researchgate acidosis lactica por metformina. Lactic acidosis is a serious but uncommon side effect of metformin use. Case report jaime zegarra 1,a, monica meza1,b,carla cornejo, willy porras, alfredo diaz 1,a, omar heredia, wilson. Early diagnosis and timely treatment are essential to decrease mortality. Pdf acidosis lactica por metformina luis castillo lopez. Early treatment with bicarbonate and continuous hemofiltration allowed a quick improvement of the patient. Lactic acidosis and distributive shock due to metformin. Metforminassociated lactic acidosis has an elevated mortality 5080% and has a specific and effective treatment. We present the case of a patient with hypertension treated with indapamide and captopril and type 2 diabetes mellitus treated with insulin and metformin. Lactic acidosis is an uncommon side effect of metformin use, which is more likely to arise in patients with certain predisposing factors. Acidosis lactica por metformina endocrinologia y nutricion.